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Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies

Enzymes, as biological catalysts, form the basis of all forms of life. How these proteins have evolved their functions remains a fundamental question in biology. Over 100 years of detailed biochemistry studies, combined with the large volumes of sequence and protein structural data now available, me...

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Detalles Bibliográficos
Autores principales: Furnham, Nicholas, Dawson, Natalie L., Rahman, Syed A., Thornton, Janet M., Orengo, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751976/
https://www.ncbi.nlm.nih.gov/pubmed/26585402
http://dx.doi.org/10.1016/j.jmb.2015.11.010