Bystander hyperactivation of preimmune CD8(+) T cells in chronic HCV patients

Chronic infection perturbs immune homeostasis. While prior studies have reported dysregulation of effector and memory cells, little is known about the effects on naïve T cell populations. We performed a cross-sectional study of chronic hepatitis C (cHCV) patients using tetramer-associated magnetic e...

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Detalles Bibliográficos
Autores principales: Alanio, Cécile, Nicoli, Francesco, Sultanik, Philippe, Flecken, Tobias, Perot, Brieuc, Duffy, Darragh, Bianchi, Elisabetta, Lim, Annick, Clave, Emmanuel, van Buuren, Marit M, Schnuriger, Aurélie, Johnsson, Kerstin, Boussier, Jeremy, Garbarg-Chenon, Antoine, Bousquet, Laurence, Mottez, Estelle, Schumacher, Ton N, Toubert, Antoine, Appay, Victor, Heshmati, Farhad, Thimme, Robert, Pol, Stanislas, Mallet, Vincent, Albert, Matthew L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752008/
https://www.ncbi.nlm.nih.gov/pubmed/26568315
http://dx.doi.org/10.7554/eLife.07916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752008/
https://www.ncbi.nlm.nih.gov/pubmed/26568315
http://dx.doi.org/10.7554/eLife.07916

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