BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice

Precise regulation of transcription is crucial for the cellular mechanisms underlying memory formation. However, the link between neuronal stimulation and the proteins that directly interact with histone modifications to activate transcription in neurons remains unclear. Brd4 is a member of the BET...

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Detalles Bibliográficos
Autores principales: Korb, Erica, Herre, Margo, Zucker-Scharff, Ilana, Darnell, Robert B., Allis, C. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752120/
https://www.ncbi.nlm.nih.gov/pubmed/26301327
http://dx.doi.org/10.1038/nn.4095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752120/
https://www.ncbi.nlm.nih.gov/pubmed/26301327
http://dx.doi.org/10.1038/nn.4095

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