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Nuclear Export of Pre-Ribosomal Subunits Requires Dbp5, but Not as an RNA-Helicase as for mRNA Export

The DEAD-box RNA-helicase Dbp5/Rat8 is known for its function in nuclear mRNA export, where it displaces the export receptor Mex67 from the mRNA at the cytoplasmic side of the nuclear pore complex (NPC). Here we show that Dbp5 is also required for the nuclear export of both pre-ribosomal subunits. Y...

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Detalles Bibliográficos
Autores principales: Neumann, Bettina, Wu, Haijia, Hackmann, Alexandra, Krebber, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752221/
https://www.ncbi.nlm.nih.gov/pubmed/26872259
http://dx.doi.org/10.1371/journal.pone.0149571