Cargando…

Low Vitamin-D Levels Combined with PKP3-SIGIRR-TMEM16J Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants

BACKGROUND: This study examined the associations of 25-hydroxyvitamin D and specific host genetic variants that affect vitamin D levels or its effects on immune function, with the risk of TB or mortality in children. METHODS: A case-cohort sample of 466 South African infants enrolled in P1041 trial...

Descripción completa

Detalles Bibliográficos
Autores principales: Gupta, Amita, Montepiedra, Grace, Gupte, Akshay, Zeldow, Bret, Jubulis, Jennifer, Detrick, Barbara, Violari, Avy, Madhi, Shabir, Bobat, Raziya, Cotton, Mark, Mitchell, Charles, Spector, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752266/
https://www.ncbi.nlm.nih.gov/pubmed/26872154
http://dx.doi.org/10.1371/journal.pone.0148649