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Network Analysis of a Comprehensive Knowledge Repository Reveals a Dual Role for Ceramide in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common cause of senile dementia. Many inflammatory factors such as amyloid-β and pro-inflammatory cytokines are known to contribute to the inflammatory response in the AD brain. Sphingolipids are widely known to have roles in the pathogenesis of inflammatory dise...

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Detalles Bibliográficos
Autores principales: Mizuno, Satoshi, Ogishima, Soichi, Kitatani, Kazuyuki, Kikuchi, Masataka, Tanaka, Hiroshi, Yaegashi, Nobuo, Nakaya, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752297/
https://www.ncbi.nlm.nih.gov/pubmed/26849355
http://dx.doi.org/10.1371/journal.pone.0148431