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Expression of Ferritin Light Chain (FTL) Is Elevated in Glioblastoma, and FTL Silencing Inhibits Glioblastoma Cell Proliferation via the GADD45/JNK Pathway

Accumulating evidence suggests that iron-associated proteins contribute to tumor initiation and development. Ferritin light chain (FTL), a key protein in iron metabolism, is associated with the survival of glioblastoma multiforme (GBM) patients; however, the molecular mechanisms underlying this asso...

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Detalles Bibliográficos
Autores principales: Wu, Tingfeng, Li, Yuntao, Liu, Baohui, Zhang, Shenqi, Wu, Liquan, Zhu, Xiaonan, Chen, Qianxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752301/
https://www.ncbi.nlm.nih.gov/pubmed/26871431
http://dx.doi.org/10.1371/journal.pone.0149361