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Neighborhood Regularized Logistic Matrix Factorization for Drug-Target Interaction Prediction

In pharmaceutical sciences, a crucial step of the drug discovery process is the identification of drug-target interactions. However, only a small portion of the drug-target interactions have been experimentally validated, as the experimental validation is laborious and costly. To improve the drug di...

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Detalles Bibliográficos
Autores principales: Liu, Yong, Wu, Min, Miao, Chunyan, Zhao, Peilin, Li, Xiao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752318/
https://www.ncbi.nlm.nih.gov/pubmed/26872142
http://dx.doi.org/10.1371/journal.pcbi.1004760