Key Role of ROS in the Process of 15-Lipoxygenase/15-Hydroxyeicosatetraenoiccid-Induced Pulmonary Vascular Remodeling in Hypoxia Pulmonary Hypertension

We previously reported that 15-lipoxygenase (15-LO) and its metabolite 15-hydroxyeicosatetraenoic acid (15-HETE) were up-regulated in pulmonary arterial cells from both pulmonary artery hypertension patients and hypoxic rats and that these factors mediated the progression of pulmonary hypertension (...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qian, Mao, Min, Qiu, Yanli, Liu, Gaofeng, Sheng, Tingting, Yu, Xiufeng, Wang, Shuang, Zhu, Daling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752324/
https://www.ncbi.nlm.nih.gov/pubmed/26871724
http://dx.doi.org/10.1371/journal.pone.0149164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752324/
https://www.ncbi.nlm.nih.gov/pubmed/26871724
http://dx.doi.org/10.1371/journal.pone.0149164

Ejemplares similares