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Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef: Results of a Randomized, Placebo-Controlled Clinical Trial

BACKGROUND: HIV-1 eradication may require reactivation of latent virus along with stimulation of HIV-1-specific immune responses to clear infected cells. Immunization with autologous dendritic cells (DCs) transfected with viral mRNA is a promising strategy for eliciting HIV-1-specific immune respons...

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Detalles Bibliográficos
Autores principales: Gandhi, Rajesh T., Kwon, Douglas S., Macklin, Eric A., Shopis, Janet R., McLean, Anna P., McBrine, Nicole, Flynn, Theresa, Peter, Lauren, Sbrolla, Amy, Kaufmann, Daniel E., Porichis, Filippos, Walker, Bruce D., Bhardwaj, Nina, Barouch, Dan H., Kavanagh, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752409/
https://www.ncbi.nlm.nih.gov/pubmed/26379068
http://dx.doi.org/10.1097/QAI.0000000000000852