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A Comparative Study of Variables Influencing Ischemic Injury in the Longa and Koizumi Methods of Intraluminal Filament Middle Cerebral Artery Occlusion in Mice

The intraluminal filament model of middle cerebral artery occlusion (MCAO) in mice and rats has been plagued by inconsistency, owing in part to the multitude of variables requiring control. In this study we investigated the impact of several major variables on survival rate, lesion volume, neurologi...

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Detalles Bibliográficos
Autores principales: Morris, Gary P., Wright, Amanda L., Tan, Richard P., Gladbach, Amadeus, Ittner, Lars M., Vissel, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752454/
https://www.ncbi.nlm.nih.gov/pubmed/26870954
http://dx.doi.org/10.1371/journal.pone.0148503