Cargando…

HMGB1 Is Involved in IFN-α Production and TRAIL Expression by HIV-1-Exposed Plasmacytoid Dendritic Cells: Impact of the Crosstalk with NK Cells

Plasmacytoid dendritic cells (pDCs) are innate sensors of viral infections and important mediators of antiviral innate immunity through their ability to produce large amounts of IFN-α. Moreover, Toll-like receptor 7 (TLR7) and 9 (TLR9) ligands, such as HIV and CpG respectively, turn pDCs into TRAIL-...

Descripción completa

Detalles Bibliográficos
Autores principales: Saïdi, Héla, Bras, Marlène, Formaglio, Pauline, Melki, Marie-Thérèse, Charbit, Bruno, Herbeuval, Jean-Philippe, Gougeon, Marie-Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752468/
https://www.ncbi.nlm.nih.gov/pubmed/26871575
http://dx.doi.org/10.1371/journal.ppat.1005407