Missense Variant in MAPK Inactivator PTPN5 Is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring

BACKGROUND: Hypertrophic scarring (HTS) is hypothesized to have a genetic mechanism, yet its genetic determinants are largely unknown. The mitogen-activated protein kinase (MAPK) pathways are important mediators of inflammatory signaling, and experimental evidence implicates MAPKs in HTS formation....

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Detalles Bibliográficos
Autores principales: Sood, Ravi F., Arbabi, Saman, Honari, Shari, Gibran, Nicole S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752497/
https://www.ncbi.nlm.nih.gov/pubmed/26872063
http://dx.doi.org/10.1371/journal.pone.0149206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752497/
https://www.ncbi.nlm.nih.gov/pubmed/26872063
http://dx.doi.org/10.1371/journal.pone.0149206

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