Cargando…

A Computational Cognitive Biomarker for Early-Stage Huntington’s Disease

Huntington’s disease (HD) is genetically determined but with variability in symptom onset, leading to uncertainty as to when pharmacological intervention should be initiated. Here we take a computational approach based on neurocognitive phenotyping, computational modeling, and classification, in an...

Descripción completa

Detalles Bibliográficos
Autores principales: Wiecki, Thomas V., Antoniades, Chrystalina A., Stevenson, Alexander, Kennard, Christopher, Borowsky, Beth, Owen, Gail, Leavitt, Blair, Roos, Raymund, Durr, Alexandra, Tabrizi, Sarah J., Frank, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752511/
https://www.ncbi.nlm.nih.gov/pubmed/26872129
http://dx.doi.org/10.1371/journal.pone.0148409