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A Computational Cognitive Biomarker for Early-Stage Huntington’s Disease
Huntington’s disease (HD) is genetically determined but with variability in symptom onset, leading to uncertainty as to when pharmacological intervention should be initiated. Here we take a computational approach based on neurocognitive phenotyping, computational modeling, and classification, in an...
Autores principales: | Wiecki, Thomas V., Antoniades, Chrystalina A., Stevenson, Alexander, Kennard, Christopher, Borowsky, Beth, Owen, Gail, Leavitt, Blair, Roos, Raymund, Durr, Alexandra, Tabrizi, Sarah J., Frank, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752511/ https://www.ncbi.nlm.nih.gov/pubmed/26872129 http://dx.doi.org/10.1371/journal.pone.0148409 |
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