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Reciprocal effects of capsaicin and menthol on thermosensation through regulated activities of TRPV1 and TRPM8

Transient receptor potential vanilloid 1 (TRPV1) is activated by elevated temperature (>42 °C), and it has been reported that cold temperature decreases capsaicin-induced TRPV1 activity. In contrast, transient receptor potential melastatin 8 (TRPM8) is activated by low temperatures and menthol, a...

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Detalles Bibliográficos
Autores principales: Takaishi, Masayuki, Uchida, Kunitoshi, Suzuki, Yoshiro, Matsui, Hiroshi, Shimada, Tadashi, Fujita, Fumitaka, Tominaga, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752590/
https://www.ncbi.nlm.nih.gov/pubmed/26645885
http://dx.doi.org/10.1007/s12576-015-0427-y