The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism

Most of the intracellular pattern recognition receptors (PRRs) reside in either the endolysosome or the cytoplasm to sense pathogen-derived RNAs, DNAs, or synthetic analogs of double-stranded RNA (dsRNA), such as poly(I:C). However, it remains elusive whether or not a pathogen-derived protein can fu...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752600/
https://www.ncbi.nlm.nih.gov/pubmed/26861016
http://dx.doi.org/10.1128/mBio.01872-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752600/
https://www.ncbi.nlm.nih.gov/pubmed/26861016
http://dx.doi.org/10.1128/mBio.01872-15

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