Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence

OBJECTIVES: Dysbiosis of the intestinal microbiota is associated with Crohn's disease (CD). Functional evidence for a causal role of bacteria in the development of chronic small intestinal inflammation is lacking. Similar to human pathology, TNF(deltaARE) mice develop a tumour necrosis factor (...

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Detalles Bibliográficos
Autores principales: Schaubeck, Monika, Clavel, Thomas, Calasan, Jelena, Lagkouvardos, Ilias, Haange, Sven Bastiaan, Jehmlich, Nico, Basic, Marijana, Dupont, Aline, Hornef, Mathias, von Bergen, Martin, Bleich, André, Haller, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Gut Microbiota
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752651/
https://www.ncbi.nlm.nih.gov/pubmed/25887379
http://dx.doi.org/10.1136/gutjnl-2015-309333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752651/
https://www.ncbi.nlm.nih.gov/pubmed/25887379
http://dx.doi.org/10.1136/gutjnl-2015-309333

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