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Detection of ALDH1 activity in rabbit hepatic VX2 tumors and isolation of ALDH1 positive cancer stem cells

BACKGROUND: Aldehyde dehydrogenase 1 (ALDH1) activity has been implicated in the therapeutic drug resistance of many malignancies and has been widely used as a marker to identify stem-like cells, including in primary liver cancer. Cancer stem cells (CSCs) are thought to play a crucial role in cancer...

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Detalles Bibliográficos
Autores principales: Gehlot, Prashasnika, Shukla, Vivek, Gupta, Sanjay, Makidon, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752741/
https://www.ncbi.nlm.nih.gov/pubmed/26873175
http://dx.doi.org/10.1186/s12967-016-0785-0