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Genome-wide studies reveal novel and distinct biological pathways regulated by SIN3 isoforms

BACKGROUND: The multisubunit SIN3 complex is a global transcriptional regulator. In Drosophila, a single Sin3A gene encodes different isoforms of SIN3, of which SIN3 187 and SIN3 220 are the major isoforms. Previous studies have demonstrated functional non-redundancy of SIN3 isoforms. The role of SI...

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Detalles Bibliográficos
Autores principales: Saha, Nirmalya, Liu, Mengying, Gajan, Ambikai, Pile, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752761/
https://www.ncbi.nlm.nih.gov/pubmed/26872827
http://dx.doi.org/10.1186/s12864-016-2428-5