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RECQ helicases are deregulated in hematological malignancies in association with a prognostic value

BACKGROUND: RECQ helicase family members act as guardians of the genome to assure proper DNA metabolism in response to genotoxic stress. Hematological malignancies are characterized by genomic instability that is possibly related to underlying defects in DNA repair of genomic stability maintenance....

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Detalles Bibliográficos
Autores principales: Viziteu, Elena, Kassambara, Alboukadel, Pasero, Philippe, Klein, Bernard, Moreaux, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752763/
https://www.ncbi.nlm.nih.gov/pubmed/26877874
http://dx.doi.org/10.1186/s40364-016-0057-4