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RECQ helicases are deregulated in hematological malignancies in association with a prognostic value
BACKGROUND: RECQ helicase family members act as guardians of the genome to assure proper DNA metabolism in response to genotoxic stress. Hematological malignancies are characterized by genomic instability that is possibly related to underlying defects in DNA repair of genomic stability maintenance....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752763/ https://www.ncbi.nlm.nih.gov/pubmed/26877874 http://dx.doi.org/10.1186/s40364-016-0057-4 |