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Effect of alirocumab on specific lipoprotein non-high-density lipoprotein cholesterol and subfractions as measured by the vertical auto profile method: analysis of 3 randomized trials versus placebo

BACKGROUND: The effect of alirocumab on potentially atherogenic lipoprotein subfractions was assessed in a post hoc analysis using the vertical auto profile (VAP) method. METHODS: Patients from three Phase II studies with low-density lipoprotein cholesterol (LDL-C) ≥2.59 mmol/L (100 mg/dL) at baseli...

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Detalles Bibliográficos
Autores principales: Toth, Peter P., Hamon, Sara C., Jones, Steven R., Martin, Seth S., Joshi, Parag H., Kulkarni, Krishnaji R., Banerjee, Poulabi, Hanotin, Corinne, Roth, Eli M., McKenney, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752766/
https://www.ncbi.nlm.nih.gov/pubmed/26872608
http://dx.doi.org/10.1186/s12944-016-0197-4