Effector function of CTLs is increased by irradiated colorectal tumor cells that modulate OX-40L and 4-1BBL and is reversed following dual blockade

BACKGROUND: Sub-lethal doses of ionizing radiation (IR) can alter the phenotype of target tissue by modulating genes that influence effector T cell activity. Previous studies indicate that cancer cells respond to radiation by up-regulating surface expression of death receptors, cell adhesion molecul...

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Detalles Bibliográficos
Autores principales: Kumari, Anita, Garnett-Benson, Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752774/
https://www.ncbi.nlm.nih.gov/pubmed/26872462
http://dx.doi.org/10.1186/s13104-016-1914-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752774/
https://www.ncbi.nlm.nih.gov/pubmed/26872462
http://dx.doi.org/10.1186/s13104-016-1914-9

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