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Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry
The mitochondrial membrane potential (Δψ(m)) is a major determinant and indicator of cell fate, but it is not possible to assess small changes in Δψ(m) within cells or in vivo. To overcome this, we developed an approach that utilizes two mitochondria-targeted probes each containing a triphenylphosph...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752821/ https://www.ncbi.nlm.nih.gov/pubmed/26712463 http://dx.doi.org/10.1016/j.cmet.2015.11.014 |