Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry

The mitochondrial membrane potential (Δψ(m)) is a major determinant and indicator of cell fate, but it is not possible to assess small changes in Δψ(m) within cells or in vivo. To overcome this, we developed an approach that utilizes two mitochondria-targeted probes each containing a triphenylphosph...

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Detalles Bibliográficos
Autores principales: Logan, Angela, Pell, Victoria R., Shaffer, Karl J., Evans, Cameron, Stanley, Nathan J., Robb, Ellen L., Prime, Tracy A., Chouchani, Edward T., Cochemé, Helena M., Fearnley, Ian M., Vidoni, Sara, James, Andrew M., Porteous, Carolyn M., Partridge, Linda, Krieg, Thomas, Smith, Robin A.J., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752821/
https://www.ncbi.nlm.nih.gov/pubmed/26712463
http://dx.doi.org/10.1016/j.cmet.2015.11.014

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