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Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction

Axially chiral compounds play an important role in areas such as asymmetric catalysis. The tyrosine click-like reaction is an efficient approach for synthesis of urazoles with potential applications in pharmaceutical and asymmetric catalysis. Here we discover a class of urazole with axial chirality...

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Detalles Bibliográficos
Autores principales: Zhang, Ji-Wei, Xu, Jin-Hui, Cheng, Dao-Juan, Shi, Chuan, Liu, Xin-Yuan, Tan, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753251/
https://www.ncbi.nlm.nih.gov/pubmed/26864510
http://dx.doi.org/10.1038/ncomms10677