Early Ovariectomy Results in Reduced Numbers of CD11c+/CD11b+ Spleen Cells and Impacts Disease Expression in Murine Lupus

Ninety percent of those diagnosed with systemic lupus erythematosus are female, with peak incidence between the ages of 15 and 45, when women are most hormonally active. Despite significant research effort, the mechanisms underlying this sex bias remain unclear. We previously showed that a functiona...

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Detalles Bibliográficos
Autores principales: Cunningham, Melissa A., Wirth, Jena R., Scott, Jennifer L., Eudaly, Jackie, Collins, Erin L., Gilkeson, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753299/
https://www.ncbi.nlm.nih.gov/pubmed/26913030
http://dx.doi.org/10.3389/fimmu.2016.00031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753299/
https://www.ncbi.nlm.nih.gov/pubmed/26913030
http://dx.doi.org/10.3389/fimmu.2016.00031

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