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Cardiac Myosin Binding Protein-C Phosphorylation Modulates Myofilament Length-Dependent Activation

Cardiac myosin binding protein-C (cMyBP-C) phosphorylation is an important regulator of contractile function, however, its contributions to length-dependent changes in cross-bridge (XB) kinetics is unknown. Therefore, we performed mechanical experiments to quantify contractile function in detergent-...

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Detalles Bibliográficos
Autores principales: Mamidi, Ranganath, Gresham, Kenneth S., Verma, Sujeet, Stelzer, Julian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753332/
https://www.ncbi.nlm.nih.gov/pubmed/26913007
http://dx.doi.org/10.3389/fphys.2016.00038