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Highly Synchronized Expression of Lineage-Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines

Human pluripotent stem cells- (hPSCs-) derived hepatocytes have the potential to replace many hepatic models in drug discovery and provide a cell source for regenerative medicine applications. However, the generation of fully functional hPSC-derived hepatocytes is still a challenge. Towards gaining...

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Detalles Bibliográficos
Autores principales: Ghosheh, Nidal, Olsson, Björn, Edsbagge, Josefina, Küppers-Munther, Barbara, Van Giezen, Mariska, Asplund, Annika, Andersson, Tommy B., Björquist, Petter, Carén, Helena, Simonsson, Stina, Sartipy, Peter, Synnergren, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753346/
https://www.ncbi.nlm.nih.gov/pubmed/26949401
http://dx.doi.org/10.1155/2016/8648356