Cancer predisposition genes: molecular mechanisms and clinical impact on personalized cancer care: examples of Lynch and HBOC syndromes

Up to 10% of cancers occur through the inherited mutation of a group of genes called cancer predisposition genes. Individuals who carry a mutant allele of these genes have an increased susceptibility to cancer. A growing number of cancer susceptibility genes are being identified, and the physiopatho...

Descripción completa

Detalles Bibliográficos
Autor principal: Wang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753377/
https://www.ncbi.nlm.nih.gov/pubmed/26616728
http://dx.doi.org/10.1038/aps.2015.89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753377/
https://www.ncbi.nlm.nih.gov/pubmed/26616728
http://dx.doi.org/10.1038/aps.2015.89

Ejemplares similares