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Oxygen Modulates the Effectiveness of Granuloma Mediated Host Response to Mycobacterium tuberculosis: A Multiscale Computational Biology Approach

Mycobacterium tuberculosis associated granuloma formation can be viewed as a structural immune response that can contain and halt the spread of the pathogen. In several mammalian hosts, including non-human primates, Mtb granulomas are often hypoxic, although this has not been observed in wild type m...

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Detalles Bibliográficos
Autores principales: Sershen, Cheryl L., Plimpton, Steven J., May, Elebeoba E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753379/
https://www.ncbi.nlm.nih.gov/pubmed/26913242
http://dx.doi.org/10.3389/fcimb.2016.00006