Asymmetric Preorganization of Inverted Pair Residues in the Sodium-Calcium Exchanger

In analogy with many other proteins, Na(+)/Ca(2+) exchangers (NCX) adapt an inverted twofold symmetry of repeated structural elements, while exhibiting a functional asymmetry by stabilizing an outward-facing conformation. Here, structure-based mutant analyses of the Methanococcus jannaschii Na(+)/Ca...

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Detalles Bibliográficos
Autores principales: Giladi, Moshe, Almagor, Lior, van Dijk, Liat, Hiller, Reuben, Man, Petr, Forest, Eric, Khananshvili, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753433/
https://www.ncbi.nlm.nih.gov/pubmed/26876271
http://dx.doi.org/10.1038/srep20753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753433/
https://www.ncbi.nlm.nih.gov/pubmed/26876271
http://dx.doi.org/10.1038/srep20753

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