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D-β-aspartyl residue exhibiting uncommon high resistance to spontaneous peptide bond cleavage

Although L-amino acids were selected as main constituents of peptides and proteins during chemical evolution, D-aspartyl (Asp) residue is found in a variety of living tissues. In particular, D-β-Asp is thought to be stable than any other Asp isomers, and this could be a reason for gradual accumulati...

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Detalles Bibliográficos
Autores principales: Aki, Kenzo, Okamura, Emiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753488/
https://www.ncbi.nlm.nih.gov/pubmed/26876027
http://dx.doi.org/10.1038/srep21594