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(99m)Tc-labelled anti-CD11b SPECT/CT imaging allows detection of plaque destabilization tightly linked to inflammation

It remains challenging to predict the risk of rupture for a specific atherosclerotic plaque timely, a thrombotic trigger tightly linked to inflammation. CD11b, is a biomarker abundant on inflammatory cells, not restricted to monocytes/macrophages. In this study, we fabricated a probe named as (99m)T...

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Detalles Bibliográficos
Autores principales: Liu, Guobing, Hu, Yan, Xiao, Jie, Li, Xiao, Li, Yanli, Tan, Hui, Zhao, Yanzhao, Cheng, Dengfeng, Shi, Hongcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753504/
https://www.ncbi.nlm.nih.gov/pubmed/26877097
http://dx.doi.org/10.1038/srep20900