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Constructing modular and universal single molecule tension sensor using protein G to study mechano-sensitive receptors

Recently a variety of molecular force sensors have been developed to study cellular forces acting through single mechano-sensitive receptors. A common strategy adopted is to attach ligand molecules on a surface through engineered molecular tethers which report cell-exerted tension on receptor-ligand...

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Detalles Bibliográficos
Autores principales: Wang, Xuefeng, Rahil, Zainab, Li, Isaac T. S., Chowdhury, Farhan, Leckband, Deborah E., Chemla, Yann R., Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753514/
https://www.ncbi.nlm.nih.gov/pubmed/26875524
http://dx.doi.org/10.1038/srep21584