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Nuclear accumulation of CDH1 mRNA in hepatocellular carcinoma cells

Expression of E-cadherin has a central role in maintaining epithelial morphology. In solid tumors, reduction of E-cadherin results in disruption of intercellular contacts. Consequently, cells lose adhesive properties and gain more invasive mesenchymal properties. Nevertheless, the mechanism of E-cad...

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Detalles Bibliográficos
Autores principales: Ghafoory, S, Mehrabi, A, Hafezi, M, Cheng, X, Breitkopf-Heinlein, K, Hick, M, Huichalaf, M, Herbel, V, Saffari, A, Wölfl, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753520/
https://www.ncbi.nlm.nih.gov/pubmed/26029826
http://dx.doi.org/10.1038/oncsis.2015.11