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Regulation of lipid synthesis by the RNA helicase Mov10 controls Wnt5a production
Expression of the Wnt ligand Wnt5a is frequently elevated in melanoma and is thought to be a critical regulator of cell movement during metastasis. However, the mechanisms regulating its expression are unknown. We find that the level of secreted Wnt5a varies by as much as 10-fold between cell lines...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753523/ https://www.ncbi.nlm.nih.gov/pubmed/26029828 http://dx.doi.org/10.1038/oncsis.2015.15 |