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Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival
Tumor cell heterogeneity poses a major hurdle in the treatment of cancer. Mammary cancer stem-like cells (MaCSCs), or tumor-initiating cells, are highly tumorigenic sub-populations that have the potential to self-renew and to differentiate. These cells are clinically important, as they display thera...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753526/ https://www.ncbi.nlm.nih.gov/pubmed/26053033 http://dx.doi.org/10.1038/oncsis.2015.8 |