Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival

Tumor cell heterogeneity poses a major hurdle in the treatment of cancer. Mammary cancer stem-like cells (MaCSCs), or tumor-initiating cells, are highly tumorigenic sub-populations that have the potential to self-renew and to differentiate. These cells are clinically important, as they display thera...

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Detalles Bibliográficos
Autores principales: Lin, C-C, Sharma, S B, Farrugia, M K, McLaughlin, S L, Ice, R J, Loskutov, Y V, Pugacheva, E N, Brundage, K M, Chen, D, Ruppert, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753526/
https://www.ncbi.nlm.nih.gov/pubmed/26053033
http://dx.doi.org/10.1038/oncsis.2015.8

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