Virus-mediated EpoR76E gene therapy preserves vision in a glaucoma model by modulating neuroinflammation and decreasing oxidative stress

BACKGROUND: Glaucoma is a complex neurodegeneration and a leading cause of blindness worldwide. Current therapeutic strategies, which are all directed towards lowering the intraocular pressure (IOP), do not stop progression of the disease. We have demonstrated that recombinant adeno-associated virus...

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Detalles Bibliográficos
Autores principales: Hines-Beard, Jessica, Bond, Wesley S., Backstrom, Jon R., Rex, Tonia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753658/
https://www.ncbi.nlm.nih.gov/pubmed/26876380
http://dx.doi.org/10.1186/s12974-016-0499-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753658/
https://www.ncbi.nlm.nih.gov/pubmed/26876380
http://dx.doi.org/10.1186/s12974-016-0499-5

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