Does cytochrome P450 liver isoenzyme induction increase the risk of liver toxicity after paracetamol overdose?

Paracetamol (acetaminophen, N-acetyl-p-aminophenol, 4-hydroxyacetanilide) is the most common cause of acute liver failure in developed countries. There are a number of factors which potentially impact on the risk of an individual developing hepatotoxicity following an acute paracetamol overdose. The...

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Detalles Bibliográficos
Autores principales: Kalsi, Sarbjeet S, Wood, David M, Waring, W Stephen, Dargan, Paul I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753969/
https://www.ncbi.nlm.nih.gov/pubmed/27147854
http://dx.doi.org/10.2147/OAEM.S24962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753969/
https://www.ncbi.nlm.nih.gov/pubmed/27147854
http://dx.doi.org/10.2147/OAEM.S24962

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