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Does cytochrome P450 liver isoenzyme induction increase the risk of liver toxicity after paracetamol overdose?
Paracetamol (acetaminophen, N-acetyl-p-aminophenol, 4-hydroxyacetanilide) is the most common cause of acute liver failure in developed countries. There are a number of factors which potentially impact on the risk of an individual developing hepatotoxicity following an acute paracetamol overdose. The...
Autores principales: | Kalsi, Sarbjeet S, Wood, David M, Waring, W Stephen, Dargan, Paul I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753969/ https://www.ncbi.nlm.nih.gov/pubmed/27147854 http://dx.doi.org/10.2147/OAEM.S24962 |
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