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Molecular chaperones: guardians of the proteome in normal and disease states

Proteins must adopt a defined three-dimensional structure in order to gain functional activity, or must they? An ever-increasing number of intrinsically disordered proteins and amyloid-forming polypeptides challenge this dogma. While molecular chaperones and proteases are traditionally associated wi...

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Detalles Bibliográficos
Autores principales: Jeng, Wilson, Lee, Sukyeong, Sung, Nuri, Lee, Jungsoon, Tsai, Francis T.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754035/
https://www.ncbi.nlm.nih.gov/pubmed/26918154
http://dx.doi.org/10.12688/f1000research.7214.1