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Enhancing the interpretation of statistical P values in toxicology studies: implementation of linear mixed models (LMMs) and standardized effect sizes (SESs)

In this paper, we compare the traditional ANOVA approach to analysing data from 90-day toxicity studies with a more modern LMM approach, and we investigate the use of standardized effect sizes. The LMM approach is used to analyse weight or feed consumption data. When compared to the week-by-week ANO...

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Detalles Bibliográficos
Autores principales: Schmidt, Kerstin, Schmidtke, Jörg, Kohl, Christian, Wilhelm, Ralf, Schiemann, Joachim, van der Voet, Hilko, Steinberg, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754325/
https://www.ncbi.nlm.nih.gov/pubmed/25724152
http://dx.doi.org/10.1007/s00204-015-1487-8