Cargando…
Enhancing the interpretation of statistical P values in toxicology studies: implementation of linear mixed models (LMMs) and standardized effect sizes (SESs)
In this paper, we compare the traditional ANOVA approach to analysing data from 90-day toxicity studies with a more modern LMM approach, and we investigate the use of standardized effect sizes. The LMM approach is used to analyse weight or feed consumption data. When compared to the week-by-week ANO...
Autores principales: | Schmidt, Kerstin, Schmidtke, Jörg, Kohl, Christian, Wilhelm, Ralf, Schiemann, Joachim, van der Voet, Hilko, Steinberg, Pablo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754325/ https://www.ncbi.nlm.nih.gov/pubmed/25724152 http://dx.doi.org/10.1007/s00204-015-1487-8 |
Ejemplares similares
-
Variability of control data and relevance of observed group differences in five oral toxicity studies with genetically modified maize MON810 in rats
por: Schmidt, Kerstin, et al.
Publicado: (2016) -
Letter in response to the letter to the editor of archives of toxicology by Woegerbauer et al. (2016)
por: Wilhelm, Ralf, et al.
Publicado: (2016) -
The Extended Statistical Analysis of Toxicity Tests Using Standardised Effect Sizes (SESs): A Comparison of Nine Published Papers
por: Festing, Michael F. W.
Publicado: (2014) -
Applying Linear Mixed Effects Models (LMMs) in Within-Participant Designs With Subjective Trial-Based Assessments of Awareness—a Caveat
por: Hesselmann, Guido
Publicado: (2018) -
Proposed criteria for the evaluation of the scientific quality of mandatory rat and mouse feeding trials with whole food/feed derived from genetically modified plants
por: Schmidt, Kerstin, et al.
Publicado: (2016)