Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A

Hepatitis C virus (HCV) utilizes autophagy to promote its propagation. Here we show the autophagy-mediated suppression of HCV replication via the endoplasmic reticulum (ER) protein SCOTIN. SCOTIN overexpression inhibits HCV replication and infectious virion production in cells infected with cell cul...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Nari, Kim, Min-Jung, Sung, Pil Soo, Bae, Yong Chul, Shin, Eui-Cheol, Yoo, Joo-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754343/
https://www.ncbi.nlm.nih.gov/pubmed/26868272
http://dx.doi.org/10.1038/ncomms10631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754343/
https://www.ncbi.nlm.nih.gov/pubmed/26868272
http://dx.doi.org/10.1038/ncomms10631

Ejemplares similares