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Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A

Hepatitis C virus (HCV) utilizes autophagy to promote its propagation. Here we show the autophagy-mediated suppression of HCV replication via the endoplasmic reticulum (ER) protein SCOTIN. SCOTIN overexpression inhibits HCV replication and infectious virion production in cells infected with cell cul...

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Detalles Bibliográficos
Autores principales:	Kim, Nari, Kim, Min-Jung, Sung, Pil Soo, Bae, Yong Chul, Shin, Eui-Cheol, Yoo, Joo-Yeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754343/ https://www.ncbi.nlm.nih.gov/pubmed/26868272 http://dx.doi.org/10.1038/ncomms10631

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