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Exendin-4 enhances expression of Neurod1 and Glut2 in insulin-producing cells derived from mouse embryonic stem cells

INTRODUCTION: Stem cells involved cell replacement therapies for type 1 diabetes mellitus is promising, yet time-consuming and inefficient. Exendin-4 is a glucagon-like peptide-1 (GLP-1) receptor agonist which has been reported to possess anti-apoptotic effects, thereby increasing β-cell mass and im...

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Detalles Bibliográficos
Autores principales: Zhao, Qiaoshi, Yang, Yuzhi, Hu, Jing, Shan, Zhiyan, Wu, Yanshuang, Lei, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754381/
https://www.ncbi.nlm.nih.gov/pubmed/26925137
http://dx.doi.org/10.5114/aoms.2016.57596