Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

Genome-wide Association Studies (GWAS) result in millions of summary statistics (“z-scores”) for single nucleotide polymorphism (SNP) associations with phenotypes. These rich datasets afford deep insights into the nature and extent of genetic contributions to complex phenotypes such as psychiatric d...

Descripción completa

Detalles Bibliográficos
Autores principales: Holland, Dominic, Wang, Yunpeng, Thompson, Wesley K., Schork, Andrew, Chen, Chi-Hua, Lo, Min-Tzu, Witoelar, Aree, Werge, Thomas, O'Donovan, Michael, Andreassen, Ole A., Dale, Anders M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754432/
https://www.ncbi.nlm.nih.gov/pubmed/26909100
http://dx.doi.org/10.3389/fgene.2016.00015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754432/
https://www.ncbi.nlm.nih.gov/pubmed/26909100
http://dx.doi.org/10.3389/fgene.2016.00015

Ejemplares similares